QUOTE(cabbagerat @ Nov 4 2003, 02:40 AM)
It is always a good idea to seperate power (mains voltage) and signal cables in seperate conduits. The reason for this is to make sure that even if the insulation on some of the cables is compromised then line voltage doesn't get applied to the signal cables. If this were to happen it would be a severe fire and safety risk. This sort of thing happens more often than you can imagine - all sorts of things tend to make holes in those nice plastic coverings on cables and wires.
Speaking as a qualified approved electrician ( now non practising ) I agree.I'm not sure what the current United Kingdom I.E.E wiring regulations specify but they are more safety conscious that many other country's.
High voltage conductors that are used in domestic installations have a amount of Resistance/ insulation needed for protecting that wire.mainly two types of protection are used for insulation - electrical and mechanical.
Electrical 7 mechnical protection ( rubber insulation ) used mainly to stop the conductors current from breaking out of the confines of the wires conductor and zapping ya in the ass!

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And mechanical protection ( metal conduits - tubes - etc etc )
Modern fuse's can use both electrical and mechanical protection to break an electrical circuit.
So by placing speaker cable next to Mains voltage cable what do you compromise?
well if any breakdown of the main cables insulation should occur lets say as a worst example in a typical UK domestic installation, you could have a speaker cable that is subject to anywhere between 5 amps to 100 Amps ( Modern showers can take this amount ) the usual cables you have for T.V's,amps,radios will have a max load usually ( due to the fuse protection ) of 5 amps or 13 amps to the plug ( for electrical protection for the electrical equipment), and 15 amps or 30 amps from the main fuse board to protect the wires/cables supplying that socket( UK only ).
Current measured in ampheres is always seeking the easiest path similar to water in a stream,if your speaker wire lay-ed next to the main cable is the path of least resistance then your nice new speakers could have a quick blast of 240 V 100 Amps.
This maybe for only Milli seconds provided the fuse breaks,though this may not cause much of a risk to your health( unless your touching metal on the audio system and have a weak heart), I'm guessing the speakers electronic components will kinda be fused and frizzle like a fly in a flame .
Just use common sense! thats mostly what electrical installation is about,don't Mix and match electrical components with hugely different voltages and currents together ,unless these components are designed and shielded specifically for that kind of installation.
I believe most speaker cable is not designed to run or be next to mains voltage cable,and even if it was it's better practice if possible to keep these things separate if @ all possible.
As for will this effect the sound you pick up with your speakers?
Dunno never tried it

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But if you begin to hear you kettle being boiled and your microwave ping! from your speakers...?that should'nt be happenning ! Just kidding.
It's the safety of your main electrical installation that matters far more than any artifacts your speakers may pick up.