QUOTE(hellokeith @ Jul 2 2008, 23:59)

I was hoping someone could explain, perhaps with some math, if multiple resampling operations are never, sometimes, or always a lossless process?
If you have perfect filters, no quantisation, no time shift - then yes.
If you have a system specifically designed to be reversible, then yes.
Otherwise, no. You can't get the same numbers back that you started with.
Typically, within the passband of the real world (i.e. imperfect) filters used, you will get the original signal back, but it will have some additional noise, and a fixed non-integer sample delay - either of which would prevent you from getting the same numbers back that you started with, but neither of which _should_ cause an audible change to the audio signal.
If you compared the original signal with the multiple resampled signal
in the analogue domain it would be near impossible to detect a difference
if you use good converters for the D/A and
if you included a low pass filter in or after the D/A that was lower than the limit of the filtering using during the resampling.
The numbers may be different, but the signal they represent is the same - just time shifted slightly, with some amplitude- (and possibly phase-) changes at the top of the frequency range (where exactly? it depends on the filters used for resampling - there might be some distortion up there too).
Of course bad resampling could wreck the whole audible range, adding aliasing, phase distortion, amplitude distortion, more noise than necessary etc.
Cheers,
David.